Invention Grant
US08415367B2 Pyrimidinylpiperidinyloxypyridinone analogues as GPR119 modulators
有权
嘧啶基哌啶氧基吡啶酮类似物作为GPR119调节剂
- Patent Title: Pyrimidinylpiperidinyloxypyridinone analogues as GPR119 modulators
- Patent Title (中): 嘧啶基哌啶氧基吡啶酮类似物作为GPR119调节剂
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Application No.: US13080758Application Date: 2011-04-06
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Publication No.: US08415367B2Publication Date: 2013-04-09
- Inventor: Dean Wacker , Stephen O'Connor , Zhenqiu Hong
- Applicant: Dean Wacker , Stephen O'Connor , Zhenqiu Hong
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Terence J. Bogie
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505

Abstract:
Novel compounds of structure Formula I: or an enantiomer, a diastereomer, or a pharmaceutically acceptable salt thereof, wherein n1, R1, R2, R3 and R4 are defined herein, are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR119 G protein-coupled receptor modulator therapy. Thus, the disclosure also concerns compositions comprising these novel compounds and methods of treating diseases or conditions related to the activity of the GPR119 G protein-coupled receptor by using any of these novel compounds or a composition comprising any of such novel compounds.
Public/Granted literature
- US20110251221A1 PYRIMIDINYLPIPERIDINYLOXYPYRIDINONE ANALOGUES AS GPR119 MODULATORS Public/Granted day:2011-10-13
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