A cell design for systems of mediated electrochemical oxidation (MEO) of materials includes inactive surface coatings, such as polyvinylidene fluoride, polypropylene, ethylene-chlorotrifluoroethylene and polytetrafluoroethylene polymers or a glass glaze or metallic oxide, on all interior surfaces of the electrochemical cell to prevent . A further cell design for systems of mediated electrochemical oxidation (MEO) included conduits for connecting plural catholyte chambers or for connecting plural anolyte chambers which are embedded within walls of a molded unibody constructed box and slots for parallel arrangement of membranes and porous electrodes.