Invention Grant
- Patent Title: Modulators of cystic fibrosis transmembrane conductance regulator
- Patent Title (中): 囊性纤维化跨膜电导调节剂的调节剂
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Application No.: US13453193Application Date: 2012-04-23
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Publication No.: US08410132B2Publication Date: 2013-04-02
- Inventor: Hayley Binch , Peter D. J. Grootenhuis , Sara S Hadida Ruah , Jinglan Zhou , Anna Hazlewood , Lev T. D. Fanning
- Applicant: Hayley Binch , Peter D. J. Grootenhuis , Sara S Hadida Ruah , Jinglan Zhou , Anna Hazlewood , Lev T. D. Fanning
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Nancy K. Brennan
- Main IPC: A61K31/4375
- IPC: A61K31/4375 ; A61P3/10 ; A61P5/18 ; A61P11/00 ; A61P25/16 ; A61P25/28 ; C07D471/04 ; C12N5/00 ; C07K1/00
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Public/Granted literature
- US20130018070A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Public/Granted day:2013-01-17
Information query
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