Invention Grant
- Patent Title: Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
- Patent Title (中): 用于预防和治疗复杂疾病及其可插入医疗器械的输送的药物组合物
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Application No.: US11990162Application Date: 2006-07-28
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Publication No.: US08410109B2Publication Date: 2013-04-02
- Inventor: Norman C. W. Wong , Henrik C. Hansen , Fabrizio S. Chiacchia , Jan O. Johansson
- Applicant: Norman C. W. Wong , Henrik C. Hansen , Fabrizio S. Chiacchia , Jan O. Johansson
- Applicant Address: CA Calgary, Alberta
- Assignee: Resverlogix Corp.
- Current Assignee: Resverlogix Corp.
- Current Assignee Address: CA Calgary, Alberta
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- International Application: PCT/US2006/029827 WO 20060728
- International Announcement: WO2007/016525 WO 20070208
- Main IPC: A61K31/497
- IPC: A61K31/497
Abstract:
The present invention relates to polyphenol-like compounds that are useful for inhibiting VCAM-1 expression, MCP-1 expression and/or SMC proliferation in a mammal. The disclosed compounds are useful for regulating markers of inflammatory conditions, including vascular inflammation, and for treatment and prevention of inflammatory and cardiovascular diseases and related disease states.
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