Invention Grant
- Patent Title: Pyridazines
- Patent Title (中): 哒嗪
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Application No.: US12768765Application Date: 2010-04-28
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Publication No.: US08410104B2Publication Date: 2013-04-02
- Inventor: Matthew C. Lucas , Andrew Thomas
- Applicant: Matthew C. Lucas , Andrew Thomas
- Applicant Address: US NJ Nutley US CA Palo Alto
- Assignee: Hoffmann-La Roche Inc.,Roche Palo Alto LLC
- Current Assignee: Hoffmann-La Roche Inc.,Roche Palo Alto LLC
- Current Assignee Address: US NJ Nutley US CA Palo Alto
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- Priority: EP09159412 20090505
- Main IPC: A61K31/501
- IPC: A61K31/501 ; C07D413/12 ; C07D413/14
Abstract:
The present invention is concerned with isoxazole-pyridazines of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful as cognitive enhancer or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.
Public/Granted literature
- US20100286159A1 PYRIDAZINES Public/Granted day:2010-11-11
Information query
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