Invention Grant
- Patent Title: Modulation of eIF4E expression
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Application No.: US13548784Application Date: 2012-07-13
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Publication No.: US08410074B2Publication Date: 2013-04-02
- Inventor: Kenneth W. Dobie , Eric G. Marcusson , Eric E. Swayze , Balkrishen Bhat , Jeremy Richard Graff
- Applicant: Kenneth W. Dobie , Eric G. Marcusson , Eric E. Swayze , Balkrishen Bhat , Jeremy Richard Graff
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; A61K31/70 ; C12Q1/68
Abstract:
Oligomeric compounds, compositions and methods are provided for modulating the expression of eIF4E. The antisense compounds may be single- or double-stranded and are targeted to nucleic acid encoding eIF4E. Methods of using these compounds for modulation of eIF4E expression and for diagnosis and treatment of diseases and conditions associated with expression of eIF4E are provided.
Public/Granted literature
- US20120283312A1 MODULATION OF EIF4E EXPRESSION Public/Granted day:2012-11-08
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