Invention Grant
- Patent Title: Biomaterial composite composition and method of use
- Patent Title (中): 生物材料复合材料的组成及使用方法
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Application No.: US13462075Application Date: 2012-05-02
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Publication No.: US08404256B2Publication Date: 2013-03-26
- Inventor: Jonathan Dempsey McCanless , Warren Ollver Haggard
- Applicant: Jonathan Dempsey McCanless , Warren Ollver Haggard
- Applicant Address: US TN Memphis
- Assignee: The University of Memphis Research Foundation
- Current Assignee: The University of Memphis Research Foundation
- Current Assignee Address: US TN Memphis
- Agency: Harris, Shelton, Hanover & Walsh
- Main IPC: A61K47/36
- IPC: A61K47/36 ; A61K35/14 ; A61K9/00 ; A61K38/18 ; A61P19/00 ; A61P29/00 ; B65D85/00

Abstract:
This invention relates to a process to facilitate osteochondral bone remodeling in a subject by inducing regeneration of this bone to a healthy, vascularized state capable of supporting the underlying hyaline cartilage of articular joints and spinal discs, both biomechanically and metabolically and to deliver a bioactive agent. This process involves the steps of: administering an effective amount of an injectable in situ curing biomaterial composite to a site. The biomaterial composite product is prepared by a process involving the steps: admixing an alginate solution with a nonporous aggregate of β-tricalcium phosphate, in a sufficient amount to initiate polymerization of the alginate solution, to form a hydrogel having from between 10 to 20 percent by volume of β-tricalcium phosphate.
Public/Granted literature
- US20120282302A1 BIOMATERIAL COMPOSITE COMPOSITION AND METHOD OF USE Public/Granted day:2012-11-08
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