Invention Grant
US08404226B2 Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs
有权
用于保护,恢复和增强响应性细胞,组织和器官的组织保护性细胞因子
- Patent Title: Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs
- Patent Title (中): 用于保护,恢复和增强响应性细胞,组织和器官的组织保护性细胞因子
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Application No.: US10520140Application Date: 2003-07-03
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Publication No.: US08404226B2Publication Date: 2013-03-26
- Inventor: Michael Brines , Anthony Cerami , Carla Cerami
- Applicant: Michael Brines , Anthony Cerami , Carla Cerami
- Applicant Address: US NY Ossining
- Assignee: The Kenneth S. Warren Institute, Inc.
- Current Assignee: The Kenneth S. Warren Institute, Inc.
- Current Assignee Address: US NY Ossining
- Agency: Jones Day
- International Application: PCT/US03/21350 WO 20030703
- International Announcement: WO2004/004656 WO 20040115
- Main IPC: A61K45/00
- IPC: A61K45/00 ; A61K38/18 ; A61K38/16

Abstract:
Methods and compositions are provided for treating a mammal having inflammation by protecting or enhancing a responsive cell, tissue, organ or body part exhibiting or associated with the inflammation, by systemic or local administration of a composition comprising a tissue protective cytokine. The invention also encompasses combination treatments comprising administering a composition comprising a tissue protective cytokine of the invention and administering at least one anti-inflammatory or least one immunomodulatory agent.
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