Provided is an optical sensor interrogation system. The optical sensor interrogation system includes: a light source unit which matches round-trip time of light and wavelength tunable cycle time of light in a resonator and emits light; a sensing unit which receives an optical signal in which a center wavelength periodically tunes, from the light source unit and tunes the center wavelength of the optical signal according to physical changes applied from the outside; and a signal processing unit which receives the optical signal reflected from the sensing unit, detects data, and images the data. In particular, the light source unit includes a delaying unit which delays the round-trip time of light and a tunable filter which tunes the wavelength of light so as to match the round-trip time of light with the wavelength tunable cycle time of light. Accordingly, a Fourier domain mode locking (FDML) wavelength swept laser, which operates at speed of several tens kHz or above, is used as a light source so that strain of a fluid, which changes in a short time interval of 0.1 msec or below, is precisely measured and thus a real-time analysis may be performed at high speed.