Invention Grant
- Patent Title: Salt of 1,3,5-triazine-2,4,6-triamine derivative
- Patent Title (中): 1,3,5-三嗪-2,4,6-三胺衍生物的盐
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Application No.: US12753415Application Date: 2010-04-02
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Publication No.: US08399663B2Publication Date: 2013-03-19
- Inventor: Junya Ohmori , Makoto Kasai , Takenori Kimura , Noritaka Hamada , Ryo Mizoguchi , Satoshi Miyamoto , Noriyuki Kawano
- Applicant: Junya Ohmori , Makoto Kasai , Takenori Kimura , Noritaka Hamada , Ryo Mizoguchi , Satoshi Miyamoto , Noriyuki Kawano
- Applicant Address: JP Tokyo
- Assignee: Astellas Pharma Inc.
- Current Assignee: Astellas Pharma Inc.
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Main IPC: C07D403/12
- IPC: C07D403/12 ; A61K31/53 ; A61P25/28

Abstract:
Anytime obtained is uniform crystal of N-(4-fluorophenyl)-N′-phenyl-N″-(pyrimidin-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine (compound A) and/or N,N′-bis (4-fluorophenyl)-N″-(pyrimidin-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine (compound B) as a medicament or a starting material for the preparation of the medicament, and provided are a fumarate of the compound A and/or the compound B having excellent stability and a novel crystal thereof. A salt of the compound A and/or the compound B with fumaric acid enables uniform crystal to be anytime obtained, and thus, it is a compound that is very useful as a medicament or a starting material for the preparation of the medicament having excellent stability.
Public/Granted literature
- US20100256151A1 NOVEL SALT OF 1,3,5-TRIAZINE-2,4,6-TRIAMINE DERIVATIVE Public/Granted day:2010-10-07
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