Invention Grant
- Patent Title: Crystalline and amorphous forms of naltrexone hydrochloride
- Patent Title (中): 盐酸纳曲酮的结晶和无定形形式
-
Application No.: US12595543Application Date: 2008-04-10
-
Publication No.: US08399475B2Publication Date: 2013-03-19
- Inventor: Gary A. Nichols , Michelle R. Menze , Anthony Mannino
- Applicant: Gary A. Nichols , Michelle R. Menze , Anthony Mannino
- Applicant Address: US MO Hazelwood
- Assignee: Mallinckrodt LLC
- Current Assignee: Mallinckrodt LLC
- Current Assignee Address: US MO Hazelwood
- International Application: PCT/US2008/004639 WO 20080410
- International Announcement: WO2008/127618 WO 20081023
- Main IPC: A61K31/485
- IPC: A61K31/485 ; C07D489/08
Abstract:
The present invention relates to novel crystalline forms of naltrexone hydrochloride including hydrated and solvated forms and a novel amorphous form. The invention also describes methods of preparing the various crystalline forms. The present invention also relates to pharmaceutical compositions containing crystalline and amorphous forms of naltrexone hydrochloride, as well as methods of treating addictive behavior by administering the pharmaceutical compositions.
Public/Granted literature
- US20100120814A1 Crystalline and Amorphous Forms of Naltrexone Hydrochloride Public/Granted day:2010-05-13
Information query
IPC分类:
