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US08399466B2 Composition for regenerative treatment of cartilage disease 失效
软骨再生治疗组合物

Composition for regenerative treatment of cartilage disease
Abstract:
A composition for regenerative treatment of cartilage disease, which comprises a PDE4 inhibitor as an active ingredient, specifically a composition comprising a PDE4 inhibitor and a biocompatible and biodegradable polymer is provided, which composition, when formulated into a form suited to administer locally to affected cartilage region, such as microsphere preparation, can provide a pharmaceutical composition showing an excellent effect in regenerative treatment of cartilage.
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