Invention Grant
- Patent Title: Compounds for the treatment of proliferative disorders
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Application No.: US13269042Application Date: 2011-10-07
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Publication No.: US08399435B2Publication Date: 2013-03-19
- Inventor: Lijun Sun , Jun Jiang , Christopher Borella , Shoujun Chen , Keizo Koya
- Applicant: Lijun Sun , Jun Jiang , Christopher Borella , Shoujun Chen , Keizo Koya
- Applicant Address: US MA Lexington
- Assignee: Synta Pharmaceuticals Corp.
- Current Assignee: Synta Pharmaceuticals Corp.
- Current Assignee Address: US MA Lexington
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Wei Song
- Main IPC: A61K31/675
- IPC: A61K31/675 ; A61K31/4439 ; A61K31/4709 ; A61K31/4725 ; A61P35/00 ; C07D275/02 ; C07D261/08 ; C07D417/10 ; C07F9/09 ; C12N5/07
Abstract:
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
Public/Granted literature
- US20120040937A1 COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS Public/Granted day:2012-02-16
Information query
