Invention Grant
US08399222B2 Compositions and methods for detecting small RNAs, and uses thereof
有权
用于检测小RNA的组合物和方法及其用途
- Patent Title: Compositions and methods for detecting small RNAs, and uses thereof
- Patent Title (中): 用于检测小RNA的组合物和方法及其用途
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Application No.: US12625609Application Date: 2009-11-25
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Publication No.: US08399222B2Publication Date: 2013-03-19
- Inventor: Amara Siva , Mark Alan Reynolds
- Applicant: Amara Siva , Mark Alan Reynolds
- Applicant Address: US CA San Diego
- Assignee: Gen-Probe Incorporated
- Current Assignee: Gen-Probe Incorporated
- Current Assignee Address: US CA San Diego
- Agent Jeffrey E. Landes
- Main IPC: C12P19/34
- IPC: C12P19/34 ; C12Q1/68

Abstract:
Compositions and methods are provided for the detection of small RNA target nucleic acids, preferably miRNA target nucleic acids, wherein the compositions and methods provide for sensitive and specific detection of the target nucleic acids. The compositions and methods include using one or more of a first amplification oligomer that is preferably an extender primer, a target capture oligomer that is preferably at least partially double stranded, a promoter primer/provider, a reverse primer that is preferably a universal primer and a detection probe. The compositions and methods are useful for diagnostics, prognostics, monitoring the effectiveness of treatment and/or determining a treatment.
Public/Granted literature
- US20100129822A1 COMPOSITIONS AND METHODS FOR DETECTING SMALL RNAS, AND USES THEREOF Public/Granted day:2010-05-27
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