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US08399017B2 Use of a matrix for orally administering sustained release magnesium, and composition containing said matrix 有权
用于口服持续释放镁的基质和含有所述基质的组合物

  • Patent Title: Use of a matrix for orally administering sustained release magnesium, and composition containing said matrix
  • Patent Title (中): 用于口服持续释放镁的基质和含有所述基质的组合物
  • Application No.: US12993678
    Application Date: 2009-05-20
  • Publication No.: US08399017B2
    Publication Date: 2013-03-19
  • Inventor: Fabienne Joanny
  • Applicant: Fabienne Joanny
  • Agency: J-Tek Law PLLC
  • Agent Jeffrey D. Tekanic
  • Priority: FR0802702 20080520
  • International Application: PCT/FR2009/000585 WO 20090520
  • International Announcement: WO2009/150323 WO 20091217
  • Main IPC: A61K9/22
  • IPC: A61K9/22
Use of a matrix for orally administering sustained release magnesium, and composition containing said matrix
Abstract:
A tablet for oral administration comprises a matrix of progressive and continuous released magnesium. For the administration of 90 to 110 parts by weight of magnesium, the matrix comprises 180 to 190 parts by weight of hydroxypropylmethylcellulose, 19.8 to 22.2 parts by weight of glyceryl behenate, 10 to 12 parts by weight of lactose and 10 to 12 parts by weight of colloidal silica. A non-enteric protective coating that slows down the gastric dissolution of the magnesium may comprise 15 to 75 parts by weight of shellac, cellulose ether or a mixture thereof. The tablet may be administered to patients in need thereof.
Abstract(Chinese):

用于口服给药的片剂包括进行性和连续释放的镁的基质。 为了给予90〜110重量份的镁，该基质包含180至190重量份的羟丙基甲基纤维素，19.8至22.2重量份的山嵛酸甘油酯，10至12重量份的乳糖和10至12重量份的 的胶体二氧化硅。 减缓镁的胃溶解的非肠溶保护涂层可包含15至75重量份的虫胶，纤维素醚或其混合物。 片剂可以施用于有需要的患者。

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