A mobile wireless communications device includes a portable housing, a transmitter carried by the portable housing and configured to modulate an input signal, and an adjustable impedance matching network coupled downstream from the transmitter. An antenna is coupled downstream from the adjustable impedance matching network, and a non-directional coupler is coupled between the adjustable impedance matching network and the antenna. A feedback receiver is coupled to the non-directional coupler to generate a feedback signal. A controller is configured to control the adjustable impedance matching network based upon the input signal and the feedback signal.