A method for reducing, in an image, motion related imaging artifacts includes obtaining a four-dimensional (4D) image dataset of a region of interest, sorting the 4D image dataset into a plurality of gates, generating an image of the region of interest using the plurality of gates, quantifying a selected feature using at least one metric, selecting a reference gate from the plurality of gates based on the quantification of the feature, and registering one or more of the plurality of gates to the reference gate to generate an image of the selected feature. A system and non-transitory computer readable medium configure to implement the method are also described herein.