A differential signaling system and a flat panel display using the same. The differential signaling system includes a first wiring and a second wiring connected to a sending end and a receiving end as a differential signal line; a termination resistor connected between the first wiring and the second wiring in the receiving end side; and a programmable compensation circuit connected to the termination resistor in parallel. The programmable compensation circuits includes n switches to receive each bit of an input digital control signal; first resistors connected between a source electrode of each of the switches and the first wiring; and second resistors connected between a drain electrode of each of the switches and the second wiring.