Invention Grant
- Patent Title: Urea and sulfamide derivatives as inhibitors of TAFIa
- Patent Title (中): 尿素和磺酰胺衍生物作为TAFIa的抑制剂
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Application No.: US12480348Application Date: 2009-06-08
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Publication No.: US08389764B2Publication Date: 2013-03-05
- Inventor: Christopher Kallus , Mark Broenstrup , Werngard Czechtizky , Andreas Evers , Markus Follmann , Nis Halland , Herman Schreuder
- Applicant: Christopher Kallus , Mark Broenstrup , Werngard Czechtizky , Andreas Evers , Markus Follmann , Nis Halland , Herman Schreuder
- Applicant Address: FR Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FR Paris
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: DE102006057413 20061206
- Main IPC: C07C275/00
- IPC: C07C275/00 ; C07C273/00 ; C07C331/00 ; C07C381/00

Abstract:
The invention relates to compounds of the formula I as defined herein, which are inhibitors of activated thrombin-activatable fibrinolysis inhibitor. The compounds of the formula I are suitable for manufacturing medicaments for the prophylaxis, secondary prevention and therapy of one or more disorders which are associated with thromboses, embolisms, hypercoagulability or fibrotic changes.
Public/Granted literature
- US20100035930A1 UREA AND SULFAMIDE DERIVATIVES AS INHIBITORS OF TAFIa Public/Granted day:2010-02-11
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