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US08389764B2 Urea and sulfamide derivatives as inhibitors of TAFIa 有权
尿素和磺酰胺衍生物作为TAFIa的抑制剂

Urea and sulfamide derivatives as inhibitors of TAFIa
Abstract:
The invention relates to compounds of the formula I as defined herein, which are inhibitors of activated thrombin-activatable fibrinolysis inhibitor. The compounds of the formula I are suitable for manufacturing medicaments for the prophylaxis, secondary prevention and therapy of one or more disorders which are associated with thromboses, embolisms, hypercoagulability or fibrotic changes.
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