Invention Grant
US08389732B2 Synthesis and regioselective substitution of 6-halo- and 6-alkoxy nicotine derivatives
失效
6-卤代和6-烷氧基尼古丁衍生物的合成和区域选择性取代
- Patent Title: Synthesis and regioselective substitution of 6-halo- and 6-alkoxy nicotine derivatives
- Patent Title (中): 6-卤代和6-烷氧基尼古丁衍生物的合成和区域选择性取代
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Application No.: US12879109Application Date: 2010-09-10
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Publication No.: US08389732B2Publication Date: 2013-03-05
- Inventor: Daniel L. Comins , Florence F. Wagner , Pauline Ondachi
- Applicant: Daniel L. Comins , Florence F. Wagner , Pauline Ondachi
- Applicant Address: US NC Raleigh
- Assignee: North Carolina State University
- Current Assignee: North Carolina State University
- Current Assignee Address: US NC Raleigh
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- Main IPC: C07D401/00
- IPC: C07D401/00 ; A61K31/44
Abstract:
The present invention provides active compounds for modulating nicotinic acetylcholine receptors and methods of making the same. The methods of preparing the active compounds utilize different intermediate compounds.
Public/Granted literature
- US20100331323A1 SYNTHESIS AND REGIOSELECTIVE SUBSTITUTION OF 6-HALO- AND 6-ALKOXY NICOTINE DERIVATIVES Public/Granted day:2010-12-30
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