Invention Grant
- Patent Title: Anti-platelet membrane glycoprotein VI monoclonal antibody
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Application No.: US13095098Application Date: 2011-04-27
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Publication No.: US08389692B2Publication Date: 2013-03-05
- Inventor: Hiroshi Takayama , Kamon Shirakawa , Shoji Furusako , Yoshitaka Hosaka , Tomokazu Matsusue , Katsuki Naitoh , Yumi Hotta , Tetsushi Kawahara , Motoyasu Honda
- Applicant: Hiroshi Takayama , Kamon Shirakawa , Shoji Furusako , Yoshitaka Hosaka , Tomokazu Matsusue , Katsuki Naitoh , Yumi Hotta , Tetsushi Kawahara , Motoyasu Honda
- Applicant Address: JP Tokyo
- Assignee: Mochida Pharmaceutical Co., Ltd.
- Current Assignee: Mochida Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Foley & Lardner LLP
- Priority: JP2005-132665 20050428; JP2005-348534 20051201; WOPCT/JP2006/301818 20060127
- Main IPC: C12P21/08
- IPC: C12P21/08
Abstract:
The present invention provides an antibody which has the following features, its active fragment, or a derivative thereof: a) It specifically binds to human platelet membrane glycoprotein VI (GPVI); b) The function to activate a platelet and/or the function to induce a thrombocytopenia in vivo are low; and c) It at least partially depletes GPVI on the platelet membrane by contacting with a platelet.
Public/Granted literature
- US20110217318A1 ANTI-PLATELET MEMBRANE GLYCOPROTEIN VI MONOCLONAL ANTIBODY Public/Granted day:2011-09-08
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