Invention Grant
US08389690B2 Antibodies to JTT-1 protein and cells secreting such antibodies
有权
JTT-1蛋白的抗体和分泌此类抗体的细胞
- Patent Title: Antibodies to JTT-1 protein and cells secreting such antibodies
- Patent Title (中): JTT-1蛋白的抗体和分泌此类抗体的细胞
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Application No.: US13023880Application Date: 2011-02-09
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Publication No.: US08389690B2Publication Date: 2013-03-05
- Inventor: Takuya Tamatani , Katsunari Tezuka
- Applicant: Takuya Tamatani , Katsunari Tezuka
- Applicant Address: JP Tokyo
- Assignee: Japan Tobacco Inc.
- Current Assignee: Japan Tobacco Inc.
- Current Assignee Address: JP Tokyo
- Agency: Fish & Richardson P.C.
- Priority: JP9-62290 19970227; JP10-62217 19980226
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; C12N5/10
Abstract:
Novel cell surface molecules recognized by monoclonal antibodies against a cell surface molecule of lymphocytic cells that play an important role in autoimmune diseases and allergic diseases have been isolated, identified, and analyzed for their functions. The cell surface molecules are expressed specifically in thymocytes, lymphocytes activated by ConA-stimulation, and peripheral blood lymphocytes, and induce cell adhesion. Antibodies against the cell surface molecules significantly ameliorate pathological conditions of autoimmune diseases and allergic diseases.
Public/Granted literature
- US20120003231A1 CELL SURFACE MOLECULE MEDIATING CELL ADHESION AND SIGNAL TRANSMISSION Public/Granted day:2012-01-05
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