Invention Grant
- Patent Title: Glycyrrhetinic acid derivatives
- Patent Title (中): 甘草次酸衍生物
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Application No.: US12308798Application Date: 2007-06-27
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Publication No.: US08389573B2Publication Date: 2013-03-05
- Inventor: Stephen H. Safe , Sudhakar Chintharlapalli , Alan McAlees , Robert McCrindle
- Applicant: Stephen H. Safe , Sudhakar Chintharlapalli , Alan McAlees , Robert McCrindle
- Applicant Address: CA Guelph, Ontario US TX College Station
- Assignee: Wellington Laboratories Inc.,The Texas A&M University System
- Current Assignee: Wellington Laboratories Inc.,The Texas A&M University System
- Current Assignee Address: CA Guelph, Ontario US TX College Station
- Agent Richard S. Echler; Michael Fenwick; Patricia L. Folkins
- International Application: PCT/CA2007/001127 WO 20070627
- International Announcement: WO2008/000070 WO 20080103
- Main IPC: A61K31/215
- IPC: A61K31/215 ; C07C69/753

Abstract:
The present invention relates to novel derivatives of glycyrrhetinic acid, compositions comprising said derivatives and their use in the treatment of conditions or diseases that benefit from an upregulation of PPAR&ggr; and/or a downregulation of the expression or activity of one or more specificity (Sp) proteins, such as cancer, diabetes and Huntington's disease.
Public/Granted literature
- US20100099760A1 Glycyrrhetinic Acid Derivatives Public/Granted day:2010-04-22
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