Invention Grant
- Patent Title: Inhibitors of protein tyrosine kinase activity
- Patent Title (中): 抑制蛋白酪氨酸激酶活性
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Application No.: US13341604Application Date: 2011-12-30
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Publication No.: US08389541B2Publication Date: 2013-03-05
- Inventor: Stephen William Claridge , Ljubomir Isakovic , Michael Mannion , Stephane Raeppel , Oscar Mario Saavedra , Frederic Gaudette , Lijie Zhan , Arkadii Vaisburg
- Applicant: Stephen William Claridge , Ljubomir Isakovic , Michael Mannion , Stephane Raeppel , Oscar Mario Saavedra , Frederic Gaudette , Lijie Zhan , Arkadii Vaisburg
- Applicant Address: CA Montreal
- Assignee: MethylGene Inc.
- Current Assignee: MethylGene Inc.
- Current Assignee Address: CA Montreal
- Agency: Wood, Phillips, Katz, Clark & Mortimer
- Main IPC: A01N43/42
- IPC: A01N43/42 ; C07D413/00
Abstract:
This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling and HGF receptor signaling. More particularly, the invention relates to compounds, compositions and methods for the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
Public/Granted literature
- US20120108628A1 INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY Public/Granted day:2012-05-03
Information query
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