Invention Grant
- Patent Title: Fused heterocyclic compounds as ion channel modulators
- Patent Title (中): 稠合杂环化合物作为离子通道调节剂
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Application No.: US12607833Application Date: 2009-10-28
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Publication No.: US08389500B2Publication Date: 2013-03-05
- Inventor: Matthew Abelman , Elfatih Elzein , Robert Jiang , Rao Kalla , Tetsuya Kobayashi , Xiaofen Li , Thao Perry , Jeff Zablocki
- Applicant: Matthew Abelman , Elfatih Elzein , Robert Jiang , Rao Kalla , Tetsuya Kobayashi , Xiaofen Li , Thao Perry , Jeff Zablocki
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Agent Francis O. Ginah; J. Ellin Hartrum
- Main IPC: A61K31/18
- IPC: A61K31/18 ; A61K31/196 ; A61K31/24 ; A61K31/41 ; A61K31/44 ; A61K31/445 ; A61K31/495 ; A61K31/5375 ; A61K31/662 ; A61P3/10 ; A61P9/00 ; A61P25/02 ; A61P25/08 ; C07C311/08 ; C07C311/14 ; C07D213/42 ; C07D213/82 ; C07D257/04 ; C07D295/13 ; C07F9/40
Abstract:
The present invention relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula (IA) or (IB): as further described herein. The invention also relates to methods for the preparation of the compounds, and to pharmaceutical compositions containing such compounds.
Public/Granted literature
- US20100113449A1 FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS Public/Granted day:2010-05-06
Information query
