Some embodiments include patterning methods. First and second masking features may be formed over first and second regions of a semiconductor base, respectively. A protective mask may be formed over the second masking features. First and second spacers may be formed along sidewall edges of the first masking features and along lateral edges of the protective mask, respectively. The protective mask and the first masking features may be removed without removing the second masking features, without removing the first spacers, and without removing the second spacers. The first spacers may be third masking features that are at a tighter pitch than the first masking features. Patterns of the second masking features and the third masking features may be transferred into the semiconductor base. Some embodiments include patterned semiconductor bases.