Invention Grant
- Patent Title: In vivo mitochondrial labeling using positively-charged nitroxide enhanced and gadolinium chelate enhanced magnetic resonance imaging
- Patent Title (中): 体内线粒体标记使用正电荷氮氧自由基增强和钆螯合增强磁共振成像
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Application No.: US12390929Application Date: 2009-02-23
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Publication No.: US08388936B2Publication Date: 2013-03-05
- Inventor: Balaraman Kalyanaraman , Joy Joseph , Kathleen Marie Schmainda , Douglas Edward Prah , Marcos Lopez , Micael J. Hardy
- Applicant: Balaraman Kalyanaraman , Joy Joseph , Kathleen Marie Schmainda , Douglas Edward Prah , Marcos Lopez , Micael J. Hardy
- Applicant Address: US WI Milwaukee
- Assignee: MCW Research Foundation, Inc.
- Current Assignee: MCW Research Foundation, Inc.
- Current Assignee Address: US WI Milwaukee
- Agency: Quarles & Brady LLP
- Main IPC: A61B5/055
- IPC: A61B5/055
Abstract:
A system and method for acquiring MR imaging data from a subject includes administering positively-charged nitroxides or gadolinium chelates for in vivo mitochondrial labeling, acquiring MR imaging data from the subject, and reconstructing an image of the subject having enhanced contrast in areas including metabolic and/or mitotic activity.
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