Invention Grant
US08388643B2 Bioabsorbable polymeric implants and a method of using the same to create occlusions
有权
生物可吸收的聚合物植入物及其使用方法产生闭塞
- Patent Title: Bioabsorbable polymeric implants and a method of using the same to create occlusions
- Patent Title (中): 生物可吸收的聚合物植入物及其使用方法产生闭塞
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Application No.: US11198587Application Date: 2005-08-05
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Publication No.: US08388643B2Publication Date: 2013-03-05
- Inventor: Yuichi Murayama , Fernando Vinuela
- Applicant: Yuichi Murayama , Fernando Vinuela
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agent Daniel L. Dawes; Marcus C. Dawes
- Main IPC: A61M29/00
- IPC: A61M29/00 ; B05D7/00 ; B28B19/00 ; C23C18/00 ; C23C20/00 ; C23C28/00 ; C23C14/14 ; C23C14/16 ; A61N1/362 ; A61B1/00

Abstract:
A embolic, bioabsorbable polymeric material (BPM) is incorporated into a coil to improve long-term anatomic results in the endovascular treatment of intracranial aneurysms. The material includes at least one biocompatible and bioabsorbable polymer and growth factors, is carried by hybrid bioactive coils and is used to accelerate histopathologic transformation of unorganized clot into fibrous connective tissue in aneurysms. An endovascular cellular manipulation and inflammatory response are elicited from implantation in a vascula location. Thrombogenicity of the biocompatible and bioabsorbable polymer is controlled by the composition of or proportioning the ratio of constituents making up the polymer. The biocompatible and bioabsorbable polymer is at least one polymer selected from the group consisting of polyglycolic acid, polyglycolic acid/poly-L-lactic acid copolymers, polycaprolactive, polyhydroxybutyrate/hydroxyvalerate copolymers, poly-L-lactide. Polydioxanone, polycarbonates, and polyanhydrides.
Public/Granted literature
- US20060058835A1 Bioabsorbable polymeric implants and a method of using the same to create occlusions Public/Granted day:2006-03-16
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