A self cleaning header assembly for use within a spray application system includes a plurality of spray guns for spraying a mix of air and liquid, e.g., an adhesive, and comprises a cleaning mechanism including one or more wash nozzles and a shroud. During a cleaning cycle, the shroud is closed and the spray guns rotate to approach the wash nozzles. The wash nozzles apply pressurized liquid, e.g., water, to the spray gun nozzles to remove excess adhesive that may affect the spray pattern and flow. After the washing cycle is complete, the spray guns are rotated to again face the target of interest and the shroud is reopened.