Mail manufacturing virtualization is performed at a centralized routing site. This includes receiving, from at least one mailing source, electronic mailing data associated with at least one mailing and determining a mail routing distribution for the received electronic mailing data. Similarly, mail manufacturing virtualization includes routing the electronic mailing data to a plurality of output centers according to the determined mail routing distribution, where the plurality of output centers are configured to generate physical mail from the electronic mailing data and facilitating sending the physical mail to at least one respective recipient.