A method and system for integration of real-time field data in chemical delivery vehicle operations is disclosed. Initially, information for a plurality of regions designated for chemical delivery is received at a command center, each of the plurality of regions having a defined boundary. Real-time and forecast environmental conditions are utilized in conjunction with prior and real-time field data to rank each of the plurality of regions. One or more chemical delivery vehicles are automatically selected and dispatched to one or more of the plurality of regions. When the one or more chemical delivery vehicles are within the defined boundary of one of the plurality of regions for chemical delivery, region specific chemical delivery procedures incorporating real-time environmental conditions are automatically calculated and initiated.