Invention Grant
US08383794B2 Conformation-selective nucleic acid inhibitors of AMPA glutamate receptors
有权
AMPA谷氨酸受体的构象选择性核酸抑制剂
- Patent Title: Conformation-selective nucleic acid inhibitors of AMPA glutamate receptors
- Patent Title (中): AMPA谷氨酸受体的构象选择性核酸抑制剂
-
Application No.: US12900636Application Date: 2010-10-08
-
Publication No.: US08383794B2Publication Date: 2013-02-26
- Inventor: Li Niu , Zhen Huang
- Applicant: Li Niu , Zhen Huang
- Agency: Heslin Rothenberg Farley & Mesiti P.C.
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/02
Abstract:
The present invention relates to novel nucleic acid ligands or aptamers that demonstrate potent and selective inhibition of the open-channel conformation of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors.
Public/Granted literature
- US20120088818A1 CONFORMATION-SELECTIVE NUCLEIC ACID INHIBITORS OF AMPA GLUTAMATE RECEPTORS Public/Granted day:2012-04-12
Information query
