Invention Grant
- Patent Title: Trisubstituted thiophenes that modulate intracellular calcium
- Patent Title (中): 调节细胞内钙的三取代噻吩
-
Application No.: US13050724Application Date: 2011-03-17
-
Publication No.: US08383670B2Publication Date: 2013-02-26
- Inventor: Gonul Velicelebi , Kenneth A. Stauderman , Jeffrey P. Whitten , Yazhong Pei , Jianguo Cao , Zhijun Wang , Evan Rogers , Brian Dyck , Jonathan Grey
- Applicant: Gonul Velicelebi , Kenneth A. Stauderman , Jeffrey P. Whitten , Yazhong Pei , Jianguo Cao , Zhijun Wang , Evan Rogers , Brian Dyck , Jonathan Grey
- Applicant Address: US CA La Jolla
- Assignee: Calcimedica, Inc.
- Current Assignee: Calcimedica, Inc.
- Current Assignee Address: US CA La Jolla
- Agency: Wilson, Sonsini, Goodrich & Rosati
- Main IPC: A61K31/38
- IPC: A61K31/38

Abstract:
Described herein are compounds of Formula (I): wherein A, J, Z, X, R1, and R4 are defined herein, and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
Public/Granted literature
- US20110212970A1 COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM Public/Granted day:2011-09-01
Information query