Invention Grant
US08383625B2 Pyrrolidinium derivatives as M3 muscarnic receptor antagonists 失效
吡咯烷鎓衍生物作为M3毒蕈碱受体拮抗剂

  • Patent Title: Pyrrolidinium derivatives as M3 muscarnic receptor antagonists
  • Patent Title (中): 吡咯烷鎓衍生物作为M3毒蕈碱受体拮抗剂
  • Application No.: US11721058
    Application Date: 2005-12-22
  • Publication No.: US08383625B2
    Publication Date: 2013-02-26
  • Inventor: Neil J PressCollingwood P Stephen
  • Applicant: Neil J PressCollingwood P Stephen
  • Applicant Address: CH Basel
  • Assignee: Novartis AG
  • Current Assignee: Novartis AG
  • Current Assignee Address: CH Basel
  • Agent Daniel Woods
  • Priority: GB0428416.2 20041224
  • International Application: PCT/EP2005/013896 WO 20051222
  • International Announcement: WO2006/066928 WO 20060629
  • Main IPC: A61K31/50
  • IPC: A61K31/50 A61K31/497
Pyrrolidinium derivatives as M3 muscarnic receptor antagonists
Abstract:
Compounds of formula (I) in salt or zwitterionic form, wherein R1, R2, R3, R4 and R5 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by the muscarinic M3 receptor. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
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