Invention Grant
- Patent Title: Methods and compositions for RNA interference
- Patent Title (中): RNA干扰的方法和组成
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Application No.: US12152837Application Date: 2008-05-16
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Publication No.: US08383599B2Publication Date: 2013-02-26
- Inventor: Gregory J. Hannon , Patrick J. Paddison , Emily Bernstein , Amy Caudy , Douglas S. Conklin , Scott Hammond
- Applicant: Gregory J. Hannon , Patrick J. Paddison , Emily Bernstein , Amy Caudy , Douglas S. Conklin , Scott Hammond
- Applicant Address: US NY Cold Spring Harbor
- Assignee: Cold Spring Harbor Laboratory
- Current Assignee: Cold Spring Harbor Laboratory
- Current Assignee Address: US NY Cold Spring Harbor
- Agency: Wilmer Cutler Pickering Hale and Dorr LLP
- Main IPC: A61K48/00
- IPC: A61K48/00
Abstract:
The present invention provides methods for attenuating gene expression in a cell using gene-targeted double stranded RNA (dsRNA). The dsRNA contains a nucleotide sequence that hybridizes under physiologic conditions of the cell to the nucleotide sequence of at least a portion of the gene to be inhibited (the “target” gene).
Public/Granted literature
- US20090193531A1 Methods and compositions for RNA Interference Public/Granted day:2009-07-30
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