Invention Grant
- Patent Title: G proteins in tumor growth and angiogenesis
- Patent Title (中): G蛋白在肿瘤生长和血管生成中的作用
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Application No.: US11805715Application Date: 2007-05-24
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Publication No.: US08383597B2Publication Date: 2013-02-26
- Inventor: Xin-Yun Huang
- Applicant: Xin-Yun Huang
- Applicant Address: US NY Ithaca
- Assignee: Cornell Research Foundation, Inc.
- Current Assignee: Cornell Research Foundation, Inc.
- Current Assignee Address: US NY Ithaca
- Agency: Schwegman, Lundberg & Woessner, P.A.
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04
Abstract:
The invention provides an agent that reduces the expression of Gα12 or Gα13 polypeptide, as well as an agent that enhances G protein Gα12 or Gα13 expression and/or activity. An agent of the invention may be used to decrease or increase G protein Gα12 or Gα13 expression and/or activity thereby to treat or prevent the onset of a disease or condition associated with Gα12 or Gα13 expression and/or activity. The invention also provides a method for screening for an anti-cancer or anti-angiogenesis agent, as well as an agent that promotes angiogenesis.
Public/Granted literature
- US20080020994A1 G proteins in tumor growth and angiogenesis Public/Granted day:2008-01-24
Information query
