Invention Grant
- Patent Title: Swellable dosage form comprising gellan gum
- Patent Title (中): 包含结冷胶的可膨胀剂型
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Application No.: US11596123Application Date: 2005-05-11
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Publication No.: US08383154B2Publication Date: 2013-02-26
- Inventor: Daniel Bar-Shalom , Lillian Slot , Gina Fischer , Pernille Høyrup Hemmingsen
- Applicant: Daniel Bar-Shalom , Lillian Slot , Gina Fischer , Pernille Høyrup Hemmingsen
- Applicant Address: DK Vaerlose
- Assignee: Egalet A/S
- Current Assignee: Egalet A/S
- Current Assignee Address: DK Vaerlose
- Agency: Foley & Lardner LLP
- Priority: DK200400755 20040511
- International Application: PCT/DK2005/000317 WO 20050511
- International Announcement: WO2005/107713 WO 20051117
- Main IPC: A61K47/36
- IPC: A61K47/36 ; A61K47/38 ; A61K47/32 ; A61K47/02 ; A61K9/00

Abstract:
A novel dosage form. The dosage form is presented in particulate form and before oral ingestion the particulate material is subjected to an aqueous medium, whereby it is converted to a semi-solid form by swelling or gelling of one or more of the components, especially of a gellan gum, of the particulate matter. The invention also relates to a vehicle for oral administration of one or more active substances, the vehicle comprising a gellan gum arranged in a configuration allowing optimal water diffusion so that upon addition of a predetermined amount of an aqueous medium, without the necessity of applying shear forces or other mixing forces, within a time period of 5 minutes or less swells and/or gels and the texture of the swelled vehicle being similar to that of a soft pudding and having a viscosity of at least about 10,000 cps as measured by a Brookfield Viscometer with a #4 LV spindle at 6 rpm and at 20-25° C. In one embodiment of the invention, the particulate matter can be molded into a desired shape or pressed onto a dispensing unit such as a spoon.
Public/Granted literature
- US20080299199A1 Swellable Dosage Form Comprising Gellan Gum Public/Granted day:2008-12-04
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