Invention Grant
- Patent Title: Process for preparing purified drug conjugates
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Application No.: US12901039Application Date: 2010-10-08
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Publication No.: US08383122B2Publication Date: 2013-02-26
- Inventor: Yong Dai , Yong Wang , Shengjin Jin , Deborah H. Meshulam , Godfrey W. Amphlett
- Applicant: Yong Dai , Yong Wang , Shengjin Jin , Deborah H. Meshulam , Godfrey W. Amphlett
- Applicant Address: US MA Waltham
- Assignee: ImmunoGen, Inc.
- Current Assignee: ImmunoGen, Inc.
- Current Assignee Address: US MA Waltham
- Agency: Leydig, Voit & Mayer, Ltd.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; G01N33/53 ; C07K16/28
Abstract:
The invention provides a process for preparing a cell-binding agent chemically coupled to a drug. The process comprises covalently attaching a linker to a cell-binding agent, a purification step, conjugating a drug to the cell-binding agent and a subsequent purification step.
Public/Granted literature
- US20110021744A1 PROCESS FOR PREPARING PURIFIED DRUG CONJUGATES Public/Granted day:2011-01-27
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