Methods are provided for preserving and restoring cranial bone flaps. In one aspect, the method to preserve a cranial bone flap includes cleaning a cranial bone flap, washing the cranial bone flap with a sterile saline solution including gentamycin, and washing the bone with a sterile saline solution including vancomycin. The cranial bone flap may be dried, wrapped, and packaged before being stored in a freezer. The fixing method may include removing the preserved cranial bone flap from a freezer and unwrapping the preserved cranial bone flap from any wrappings. A previous wound may be opened for insertion of the preserved cranial bone flap. The preserved cranial bone flap may be washed with a sterile saline solution including gentamycin and a sterile saline solution including vancomycin. The edges of the previous wound may be refreshed by nipping free margins to expose diploic spaces, and the preserved cranial bone flap may be fixed in place within the previous wound.