A liquid ejection device includes a liquid ejection head and a capping mechanism. The liquid ejection head includes nozzles for ejecting a liquid. The capping mechanism covers the nozzles and receiving the liquid, the capping mechanism being selectively disposed in a contacting state in which the capping mechanism contacts with a nozzle formation surface of the liquid ejection head or in a separated state in which the capping mechanism is separated from the nozzle formation surface. The capping mechanism includes a cap member forming a space in which openings of the nozzles are hermetically sealed in the contacting state, and a pressurizing unit configured to increase pressure in an inner space surrounded by the nozzle formation surface and an inner surface of the cap member.