A power-off control circuit adapted in a LCD panel comprising a gate pulse modulator and a level shifter is provided. The power-off control circuit comprises a logic gate and a control switch. The logic gate comprises a first input to receive an internal power supply, a second input to receive a power state signal and a logic output to generate a control signal. When the power supply is on, the internal power supply is on and the power state signal is in a first state to make the control signal turn off the control switch. When the power supply is off, the internal power supply is on and the power state signal is in a second state to make the control signal turn on the control switch to make the gate pulse modulator makes pixels of a pixel array to perform a discharge activity.