Invention Grant
- Patent Title: Phenyl-isoxazol-3-ol derivative
- Patent Title (中): 苯基异恶唑-3-醇衍生物
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Application No.: US12516025Application Date: 2007-11-29
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Publication No.: US08367708B2Publication Date: 2013-02-05
- Inventor: Noriaki Hashimoto , Yasuhiro Sasaki , Chisato Nakama , Makoto Ishikawa
- Applicant: Noriaki Hashimoto , Yasuhiro Sasaki , Chisato Nakama , Makoto Ishikawa
- Applicant Address: JP Tokyo
- Assignee: MSD K.K.
- Current Assignee: MSD K.K.
- Current Assignee Address: JP Tokyo
- Agent Kenrick L. Vidale; John C. Todaro
- Priority: JP2006-325220 20061201
- International Application: PCT/JP2007/073099 WO 20071129
- International Announcement: WO2008/066131 WO 20080605
- Main IPC: A01N43/76
- IPC: A01N43/76 ; A01N43/64 ; A01N43/18 ; A01N43/06 ; A01N43/16 ; A01N43/08 ; A61K31/42 ; A61K31/41 ; A61K31/54 ; A61K31/38 ; A61K31/35 ; A61K31/34

Abstract:
The present invention relates to a compound represented by formula (I), which has a GPR120 agonist action and thus is useful for treatment of diabetes mellitus or hyperlipidemia, or a pharmaceutically acceptable salt thereof. In the formula, (AA) represents a phenyl or the like, which may be substituted with a lower alkoxy group or the like; (BB) represents a divalent group or the like, derived by removal of two hydrogen atoms from a benzene which may be substituted with a halogen atom or the like; X represents a spacer having a main chain composed of 1-8 carbon atoms wherein 1-3 carbon atoms in the main chain may be substituted with an oxygen atom or the like; and Y represents a hydrogen atom or the like.
Public/Granted literature
- US20100130559A1 NOVEL PHENYL-ISOXAZOL-3-OL DERIVATIVE Public/Granted day:2010-05-27
Information query
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