Invention Grant
- Patent Title: Phosphoinositide 3-kinase inhibitors with a zinc binding moiety
- Patent Title (中): 具有锌结合部分的磷酸肌醇3-激酶抑制剂
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Application No.: US12684594Application Date: 2010-01-08
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Publication No.: US08367663B2Publication Date: 2013-02-05
- Inventor: Xiong Cai , Haixiao Zhai , Cheng-Jung Lai , Changgeng Qian
- Applicant: Xiong Cai , Haixiao Zhai , Cheng-Jung Lai , Changgeng Qian
- Applicant Address: US MA Lexington
- Assignee: Curis, Inc.
- Current Assignee: Curis, Inc.
- Current Assignee Address: US MA Lexington
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore, Esq.
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D413/14
Abstract:
The instant application relates to deazapurines, thienopyrimidines and furopyrimidines with zinc-binding moiety based derivatives and their use in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.
Public/Granted literature
- US20100222343A1 PHOSPHOINOSITIDE 3-KINASE INHIBITORS WITH A ZINC BINDING MOIETY Public/Granted day:2010-09-02
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