Invention Grant
- Patent Title: Modulators of cystic fibrosis transmembrane conductance regulator
- Patent Title (中): 囊性纤维化跨膜电导调节剂的调节剂
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Application No.: US12643188Application Date: 2009-12-21
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Publication No.: US08367660B2Publication Date: 2013-02-05
- Inventor: Hayley Binch , Dennis Hurley , Lev T. D. Fanning , Peter D. J. Grootenhuis , Martyn Botfield , Fredrick Van Goor
- Applicant: Hayley Binch , Dennis Hurley , Lev T. D. Fanning , Peter D. J. Grootenhuis , Martyn Botfield , Fredrick Van Goor
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Nancy K. Brennan
- Main IPC: C07D265/36
- IPC: C07D265/36 ; A61K31/538
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using such CFTR modulators.
Public/Granted literature
- US20100168094A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Public/Granted day:2010-07-01
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