Invention Grant
US08367360B2 Method of screening for inhibitors of tau protein phosphororylation by tyrosine kinase c-Abl
有权
筛选酪氨酸激酶c-Abl的tau蛋白磷酸化抑制剂的方法
- Patent Title: Method of screening for inhibitors of tau protein phosphororylation by tyrosine kinase c-Abl
- Patent Title (中): 筛选酪氨酸激酶c-Abl的tau蛋白磷酸化抑制剂的方法
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Application No.: US11630720Application Date: 2005-06-21
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Publication No.: US08367360B2Publication Date: 2013-02-05
- Inventor: Malcolm Ward , Helen Byers , Brian Henry Anderton , Pascal Derkinderen , Christopher Hugh Reynolds , Ritchie Williamson
- Applicant: Malcolm Ward , Helen Byers , Brian Henry Anderton , Pascal Derkinderen , Christopher Hugh Reynolds , Ritchie Williamson
- Applicant Address: GB Surrey GB London
- Assignee: Proteome Sciences plc,King's College London
- Current Assignee: Proteome Sciences plc,King's College London
- Current Assignee Address: GB Surrey GB London
- Agency: Dann, Dorfman, Herrell and Skillman, PC
- Agent Patrick J. Hagan
- International Application: PCT/GB2005/002475 WO 20050621
- International Announcement: WO2005/123048 WO 20051229
- Main IPC: C12Q1/48
- IPC: C12Q1/48
Abstract:
The present invention provides methods of screening for candidate compounds useful in the treatment of Alzheimer's disease and related conditions by inhibiting specific phosphorylation of tau protein by tyrosine kinase c-Abl.
Public/Granted literature
- US20080103107A1 Screening Methods Public/Granted day:2008-05-01
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