Invention Grant
- Patent Title: Methods for detecting TCR-gamma gene rearrangement
- Patent Title (中): 检测TCR-γ基因重排的方法
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Application No.: US12491170Application Date: 2009-06-24
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Publication No.: US08367330B2Publication Date: 2013-02-05
- Inventor: Maher Albitar
- Applicant: Maher Albitar
- Applicant Address: US DE Wilmington
- Assignee: Quest Diagnostics Investments Incorporated
- Current Assignee: Quest Diagnostics Investments Incorporated
- Current Assignee Address: US DE Wilmington
- Agency: Foley & Lardner LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The invention provides methods for detection of TCR-γ nucleic acid in acellular body fluid. The methods can be used to detect the TCR-γ gene rearrangement in acellular body fluid. The detection of TCR-γ gene rearrangement is useful in determination of clonality of T-cell population. The invention is useful in the diagnosis of lymphoproliferative disorder.
Public/Granted literature
- US20100159456A1 METHODS FOR DETECTING TCR-GAMMA GENE REARRANGEMENT Public/Granted day:2010-06-24
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