Invention Grant
- Patent Title: Analytical method involving detection of an exciplex
- Patent Title (中): 涉及检测激素复合物的分析方法
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Application No.: US10554266Application Date: 2004-04-23
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Publication No.: US08367323B2Publication Date: 2013-02-05
- Inventor: Kenneth T. Douglas , Elena V. Bichenkova , Hannah Savage , Alireza Sardarian
- Applicant: Kenneth T. Douglas , Elena V. Bichenkova , Hannah Savage , Alireza Sardarian
- Applicant Address: GB Manchester
- Assignee: The University of Manchester
- Current Assignee: The University of Manchester
- Current Assignee Address: GB Manchester
- Agency: Nixon & Vanderhye P.C.
- Priority: GB0309396.0 20030425
- International Application: PCT/GB2004/001803 WO 20040423
- International Announcement: WO2004/097043 WO 20041111
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/00 ; G01J3/42
Abstract:
The invention relates to the use of an organic solvent selected from 2,2,2-trifluoroethanol, ethylene glycol or ethylene glycol dimethyl ether for enhancing formation, potential formation, fluorescence and/or detection of an exciplex. The invention is applicable particularly to nucleic acid hybridisation assay using two polynucleotide probes that will hybridise to a target nucleic acid. Each probe is labelled with one of two partners capable of forming an exciplex such that, on photoirradiation, the exciplex is formed when the probes are hybridised to the target nucleic acid.
Public/Granted literature
- US20060263782A1 Exciplexes Public/Granted day:2006-11-23
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