Invention Grant
US08367060B2 Pharmaceutical composition containing arazyme for the prevention of liver dysfunction
有权
含有arazyme用于预防肝功能障碍的药物组合物
- Patent Title: Pharmaceutical composition containing arazyme for the prevention of liver dysfunction
- Patent Title (中): 含有arazyme用于预防肝功能障碍的药物组合物
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Application No.: US13234847Application Date: 2011-09-16
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Publication No.: US08367060B2Publication Date: 2013-02-05
- Inventor: Ho-Yong Park , Kwang-Hee Son , Dong-Ha Shin , Kyu-Shik Jeong
- Applicant: Ho-Yong Park , Kwang-Hee Son , Dong-Ha Shin , Kyu-Shik Jeong
- Applicant Address: KR Daejeon
- Assignee: Insect Biotech Co., Ltd.
- Current Assignee: Insect Biotech Co., Ltd.
- Current Assignee Address: KR Daejeon
- Agency: Lucas & Mercanti, LLP
- Main IPC: A61K38/48
- IPC: A61K38/48
Abstract:
The present invention relates to a composition and a method for the treatment of liver dysfunction which contains administration of a composition containing arazyme as an active ingredient, more precisely arazyme produced by Aranicola proteolyticus. The arazyme of the present invention inhibits apoptosis in injured liver cells, increases SMP30 expression, inhibits P-smad3 expression and protects the liver by inhibiting liver injury around the central vein region. Therefore, the arazyme of the invention can be effectively used as a composition for the treatment of liver dysfunction.
Public/Granted literature
- US20120003205A1 PHARMACEUTICAL COMPOSITION CONTAINING ARAZYME FOR THE PREVENTION OF LIVER DYSFUNCTION Public/Granted day:2012-01-05
Information query
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