An information handling system mezzanine circuit board disposed in a parallel configuration over a motherboard is selectively coupled and de-coupled at the motherboard with a retraction and latching device that translates retraction force applied at an accessible actuation portion to push upward from below the mezzanine circuit board. A retraction portion of the retraction and latching device provides an upward force at the bottom surface of the mezzanine circuit board to separate the mezzanine circuit board connector from the motherboard connector so that an end user can lift the mezzanine circuit board away from the motherboard.