Systems, methods, and computer products for just-in-time compilation for virtual machine environments for fast applications start-up and maximal run-time performance. Exemplary embodiments include a just in time compilation method for a virtual machine environment coupled to a memory, including identifying a program structure for compilation, creating a low optimization compiled version of the program structure that is relocatable in the memory, storing into a persistent cache the low optimization compiled version of the program structure that is relocatable and relocating the low optimization compiled version of the program structure into a virtual machine address space in the memory, wherein relocating the low optimization compiled version of the program structure includes transforming the low optimization compiled version to a compiled version with fixed addresses in the memory that can be executed.